Sydney Dermatology is located in the Park House building on Macquarie Street, near the corner with Hunter Street. The clinic is positioned opposite the NSW State Library and NSW Parliament House, making it easily accessible by public transport or car.

The clinic is just 150 metres from Martin Place Station, providing quick and convenient access. It is also within a 15-minute walk from both Wynyard Station and St James Station, offering additional options for those travelling from different parts of Sydney.

Numerous bus routes run along Elizabeth Street, Castlereagh Street, and near Wynyard Station, all within easy walking distance of the clinic. These services connect from the Eastern Suburbs, Inner West, and North Shore, ensuring frequent access throughout the day.

If you are driving, several parking options are available nearby:

• Domain Car Park – large public car park within walking distance of the clinic.
• Sydney Hospital Car Park – centrally located and convenient for medical visits.
• St Mary’s Cathedral Parking – additional spaces available within a short walk.
• Park House Building Parking – limited on-site parking is available but at a premium rate.